经皮椎体成形术治疗椎体良恶性病变(临床应用35例报告)-东南大学学报医学版

经皮椎体成形术治疗椎体良恶性病变(临床应用35例报告)

单位：东南大学附属中大医院放射科,江苏南京,210009

分类号：R815, R738.1

出版年·卷·期（页码）：2002·21·第一期（98-102）

摘要：

目的:探讨经皮椎体成形术(PVP)在治疗椎体肿瘤和椎体压缩性骨折中的作用.方法:用PVP术治疗35例48个椎体病变,包括椎体恶性肿瘤22例、压缩性骨折8例、椎体血管瘤3例、骨髓瘤1例和其它病变1例.PVP在C臂X线机或C臂X线机与CT组合机监视下进行,聚甲基丙烯酸甲酯(PMMA)用量为2～8ml.随访时间为1～12个月,平均(7.5±4.2)个月.结果:PVP对椎体良恶性镇痛有效率达94.29%,其中完全缓解(CR)为71.43%(25/35),部分缓解(PR)为22.86%(8/35).无一例出现PVP后椎体塌陷加重或发生新的压缩,未发生严重并发症.结论:PVP治疗椎体良恶性病变安全,近期疗效可靠.

Objective To evaluate the effectiveness of percutaneous vertebroplasty (PVP) for pain relief and spinal stabilization in patient with vertebral lesions.Methods PVP was performed in 35 consecutive patients with 48 vertebrae.Twenty two patients had metastatic neoplasms,8 had osteoporotic compression fractures,1 had traumatic compression fracture,3 had hemangiomas,1 had multiple myelomas,and 1 had unknown lesion.All patients had severe pain and failed to relieve with me~dical or other conservative therapies.The follow up lasted 1～12 months with an average of (7.5±4.2) months.PVP procedures were undergone guided by CT plus C arm fluoroscopy or fluoroscopy only. A range from 2 to 8 ml of polymethyl methacrylate(PMMA) was injected per vertebra.Results complete relief (CR) and a partial relief (PR) were obtained in 71.43% and 22.86%,respectively.No further vertebral compression occurred in all patients.No major complications occurred in this series, except asymptomatic PMMA leak around vertebrae demonstrated by CT.Conclusion PVP brings a significant pain relief in both benign and malignant lesions in a short term of follow up.PVP seems to be useful for spinal stabilization in these patients.

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