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上尿路移行细胞癌术后再发膀胱癌
作者:孙浩 马克钧 秦剑影 潘鹏 唐爱国 徐强 蒋国波 
单位:镇江医学院附属医院,泌尿外科,
关键词:上尿路 移行细胞癌 膀胱癌 
分类号:R737.11
出版年·卷·期(页码):2001·20·第四期(262-263)
摘要:

目的:探讨上尿路移行细胞癌术后再发膀胱癌的特点.方法:对98例上尿路移行细胞癌中术后再发膀胱癌24例进行临床回顾性分析.结果:上尿路移行细胞癌行肾输尿管膀胱袖状切除术后膀胱癌再发率低于肾输尿管切除者,两组比较差异有极显著性意义(P< 0.01);上尿路移行细胞癌合并膀胱癌、肿瘤恶性程度高及输尿管下段癌其术后膀胱癌的再发率高,再发时间多在术后3年以内.结论:肾输尿管膀胱袖状切除术是上尿路移行细胞癌最有效的治疗方法,术后定期复查膀胱镜和膀胱抗癌药灌注很重要.

Objective  To study the recurrent bladder carcinoma after resection of upper urinary tract transitional cell carcinoma.Method  24 cases of recurrent bladder carcinoma out of 98 cases of postoperative upper urinary tract carcinoma were analyzed.Results  The postoperative recurreut rate of bladder carcinoma with total nephroureterectomy combined with excision of bladder cuff was lower than that of nephroureterectomy(  P  &lt;0.01);In the cases of upper urinary tract carcinoma associated with bladder carcinoma,higher grade malignancy and lower ureter carcinoma the recurrence rate was higher and usually occurred within 3 years.Conclusions  The most effective treatment is total nephroureterectomy combined with excision of bladder cuff, periodic cystoscopy and vesical instillation of anticancer drug is necessary.

参考文献:

[1] 顾方六. 尿路上皮性肿瘤, 1993
[2] Nishimura K, SHIMIZU K, IWASAKI A, et al.. Clinicopathological study on uppe r urinary tract tumors and associated bladder tumor. 1995. doi:10.1159/000282768
[3] 孔垂泽, 张铭铮, 刘同才. 肾盂输尿管癌术后再发尿路上皮癌. 中华泌尿外科杂志1994(4)
[4] SAKAMOTO N, NATIO S, KOTOH S. Recurrence of bladder tumors foll owing surgery for transitional cell carcinoma of the upper urinary tract, 1991
[5] 李黎明, 强万明, 韩树楠. 尿路上皮多器官癌发生机理探讨. 中华泌尿外科杂志2001(6)
[6] 李龙承, 张旭. 泌尿外科手术图谱, 1996
[7] VALDIVIA URIA J G, LOPEZ J A, BAYOOCHOA A. Endoscopic ureterect omy, 1991
[8] 洪宝发, 王晓雄, 肖序仁. 肾输尿管全长切除治疗肾盂输尿管癌. 中华泌尿外科杂志2000(6) 

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