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原发性先天性胆管囊肿癌变7例的诊断与治疗
作者:史留斌1 彭淑牖1 彭承宏1 吴育连1 刘颖斌1 杨德同2 嵇振岭2 高乃荣2 陈怀仁2 
单位:1.浙江大学医学院附属第二医院,外科,; 2.东南大学附属中大医院,普外科,
关键词:胆管囊肿 癌变 胆道外科手术 诊断 
分类号:R657.4
出版年·卷·期(页码):2001·20·第四期(255-257)
摘要:

目的:总结20年来7例原发性胆管囊肿癌变的诊断及治疗经验.方法:对1980~2000年间收治的7例原发性胆管囊肿癌变病人的临床资料进行回顾性分析.结果与结论癌变6例位于囊壁,1例侵及胰腺,术后病理结果为腺癌.对先天性胆管囊肿病人推荐行新的预防癌变的手术方式,术中冰冻切片检查有助于确诊,对侵及胰腺的病例考虑行囊肿切除及胰十二指肠切除术.

Objective  To summarize the experience of diagnosis and treatment of malignant change in 7 patients with primary congenital cyst of common bile duct in the past 20 years.Method  The clinical data of 7 patients admitted from 1980 to 2000 was analyzed retrospectively.Results and conclusions  The site of 6 cases with carcinoma was on the cyst wall,which 1 case spreaded to the pancreas.The pathologic feature of this disease was malignancy,most of which was adenocarcinoma.A new procedure which can prevent from malignance of congenital cyst of common bile duct is recommended.Intraoperative frozen section examination is helpful to comfirm diagnosis.Cystectomy with pancreatoduodenectomy would be done in the cases spreading to the pancreatc head.

参考文献:

[1] IRWIN S T, MORRISON J E. Congenital cyst of common bile d uct containing sto nes and underlying cancerious change. 1944. doi:10.1002/bjs.18003212614
[2] 杨德同, 史留斌, 王正悦. 先天性胆总管囊肿内引流术后癌变, 1997(1)
[3] TODANI T, WATANABE Y, NARUSUE M. Congenital bile duct cysts cla ssific ation operative procedures and review of thirty-seven cases including cancer a rising from choledochal cyst, 1977
[4] Chijiiwa K, KOGA A. Surgical management and long-term follow-up of patients with choledochal cysts, 1993
[5] Kobayashi S, ASANO T, YAMASAKI M. Risk of bile duct cancinogen esis af ter excision of extrahepatic bile ducts in pancreaticobiliary maljunction. 1999. doi:10.1016/S0039-6060(99)70036-X
[6] Komi M, TAMURA T, MIYOSHI Y. Nationwide survey of cases of chol edochal cyst Analysis of coexistent anomalies complications and surgical treatment in 645 cases, 1984
[7] Ishibashi T, KASAHARA K, YASUDA Y. Malignant change in the bili ary tra ct after excision of choledochal cyst, 1999
[8] 彭淑牖, 江献川, 彭承宏. 提高肝门胆管癌切除率的探讨, 1996(1)
[9] 徐少明. 先天性胆管扩张症并发癌变, 1994(5)
[10] 彭承宏, 彭淑牖, 刘颖斌. 先天性胆总管囊肿癌变的防治, 1999(11) 

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