晚期妊娠两种引产方法的效果观察-东南大学学报医学版

晚期妊娠两种引产方法的效果观察

单位：张家界铁路医院妇产科,

分类号：R719.31

出版年·卷·期（页码）：2001·20·第二期（111-113）

摘要：

目的：探讨米索前列醇用于晚期妊娠引产的安全性及效果。方法：将80例妊娠37～42+2周，有引产指征的初产妇随机分成米索前列醇组(40例)和催产素组(40例)，分别用米索前列醇25μg含服引产及小剂量催产素静脉滴注引产。结果：米索前列醇晚期引产的有效率显著高于对照组(P<0.05)，米索前列醇组用药至分娩时间总产程显著短于对照组(P<0.05)，两组新生儿情况比较无显著性差异(P>0.05)。结论：晚期妊娠引产选用米索前列醇含服是一种方便、有效、安全的引产方法。

Objective To determine the efficacy and safety of misoprostol as an induction agent for the initiation of labour in women at term.Methods Eighty pregnant women in 37～42 +2 gestational weeks,who had clear clinical indications for labour induction were randomly divided into two groups.Pregnant women in group A( n =40) were induced for the initiation of labour with misoprostol,while the women in group B( n =40) were induced for initiation of labour with oxytocin.Results Spontaneous delivery rate of group A was significantly higher than that of group B( P <0.005).Total times of delivery were shorter in group A than in group B( P <0.05).Neonatal prognosis did not show any significant differences between the two groups.Conclusion Misoprostol is a safe,convenient,efficient induce agent for initiation of labour at term.

参考文献：

[1] 戴钟英. 前列腺素在足月妊娠引产中的应用, 1999(5)
[2] 余江, 张进, 宋肯峰. 米索前列醇在妇产科临床的应用. 中华妇产科杂志1998(1)
[3] 赵光俊, 张启兰, 杜娟. 米索前列醇用于晚期妊娠引产的临床研究, 1997(2)

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