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误诊为纯红再障的5qˉ综合征一例
作者:高冲 高雪芝 丁家华 金宝翠 
单位:南京铁道医学院附属医院,江苏南京,210009
关键词:再生障碍性贫血 骨髓增生异常综合征 
分类号:R556.5, R551.3
出版年·卷·期(页码):2000·19·第三期(195-196)
摘要:

目的:探讨骨髓增生异常综合征(MDS)诊断问题.方法:回顾分析1例误诊为纯红再障的5qˉ综合征的原因,并复习国内外有关文献.结果:骨髓细胞形态学检查有无病态造血,不是诊断或排除MDS的唯一依据.结论:为了提高MDS诊断率,除骨髓细胞形态学检查外,尚需结合骨髓病理和骨髓细胞染色体分析的结果.

参考文献:

[1] Van den Berghe H, Cassiman J J, David G. Distinct haematological disorder with deletion of the long arm of no.5 chromosome. 1974. doi:10.1038/251437a0
[2] Sokal G, Michaux J L, Van den Berghe H. A new hematological syndrome with distinct karyotype:the 5q chromosome, 1975
[3] Boultwood J, Lewis S, Wainscoat J S. The 5q-syndrome, 1994
[4] Mathews P, Tefferi A, Dewald G W. The 5q-syndrome:a single institution study of 43 consecutive patients, 1993
[5] Bennet J M, Catovsky D, Daniel M T. Proposals for the classification of the myelodysplastic syndrome, 1982
[6] Koudies P A, Bennett J M. Morphology and classification of the myelodysplastic syndromes and their pathologic variants, 1996
[7] Bain B J. The bone marrow aspirate of healthy subjects, 1996
[8] 解新良, 庞辉, 马志峰. 儿童纯红细胞再生障碍性贫血转化为急性白血病一例. 中华血液学杂志1999(11)
[9] Robert J, Charles K M, Sabo P G. The pathophysiology of pure red cell aplasia implications for therapy, 1996
[10] Greenberg P, Christopher C, Michelle M. International scoring system for evaluating prognosis in myelodysplastic syndromes. 1997
[11] 浦权, 浦杰. 骨髓增生异常综合征的基础和临床, 1996  

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