胰腺癌各种外科术式的利弊-东南大学学报医学版

胰腺癌各种外科术式的利弊

作者：Helmut Friess¹ 刘胜利² J(o)rg Kleeff¹ 嵇振岭² 汤文浩² Markus W. Büchler¹

单位：1.Department of Visceral and Transplantation Surgery,University of Bern,Switzerland； 2.南京铁道医学院附属医院普通外科,江苏南京,210009

分类号：R735.9

出版年·卷·期（页码）：2000·19·第三期（179-183）

摘要：

目的:对治疗胰腺癌不同手术方法进行比较,并总结相关经验.方法:讨论目前治疗胰腺癌的各种手术方法,包括Whipple手术、保留幽门的胰十二指肠切除术、胰腺次全和全切术、区域性胰腺切除术以及广泛的淋巴结清扫等.结果:尚无任何其它术式能改善患者生存时间、死亡率和可切除率.结论:尽管外科手术治疗胰腺癌已取得一些进展,但总的预后仍难以令人满意.对于治疗胰腺癌,外科医生很可能仍保持原有术式的选择.

Objective In the present overview,the different surgical approaches for the resection of pancreatic cancer were compared and our experience with these techniques was presented.Method Surgical procedures,including the Whipple resection,pylorus preserving resection, total and subtotal pancreatectomies,regional pancreatectomy and the extended lymph node resection, were discussed.Result Studies have shown that no operation seems to produce significantly improved results in terms of survival, mortality and resection rates compared to the standard Whipple and pylorus?preserving duodenopancreatectomy.Conclusion Despite the progress in the surgical treatment of pancreatic cancer,the overall prognosis following resection remains unsatisfying.Surgery will most likely remain the primary option for the treatment of pancreatic cancer.

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