Objective  To investigate the change in spectrum of inpatients with hepatic diseases in hepatic hospital,to analyze the critical causes of the diseases,and to diagnose the liver cancer in patients with high likelihood in the early stage.Method  25?840 inpatients with hepatic diseases were reviewed.Results  (1)There are men (  83.54%  ) and women (16.46%) of 25?840 inpatients with hepatic diseases,among whom 41.55% suffered acute hepatitis,  30.62%   chronic hepatitis,22.08% hepatic cirrhosis,5.75% liver cancer,respectively.(2)The rate of youth patients with chronic hepatitis raised to 68.48%(5?419/7?913).The proportion of middle aged patients with acute hepatitis obviously reduced,while that with hepatic cirrhosis quickly elevated to 54.34%(3?100/5?705).The proportion of elderly patients with hepatic cirrhosis or liver cancer is higher,in which are 21.00% with liver cancer.(3)Compared with the spectrum of hepatic diseases during the last five years,the number of patients with acute hepatitis reduced,that of chronic hepatitis,hepatic cirrhosis and liver cancer kept rising,and the proportion of liver cancer was rising.Conclusion  In hepatic hospital,the number of youth and middle aged patients with chronic hepatitis,hepatic cirrhosis and liver cancer are quickly increasing.Patients with chronic hepatitis should be monitored,so that the liver cancer are found out and diagnosed in the early stage.The youth and middle aged patient with chronic hepatitis should be treated with anti  viral and anti  fibrotic medicine,to hold up the development from chronic hepatitis to hepatic cirrhosis or liver cancer.