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BRAF基因突变与消化道肿瘤
作者:程张军 石欣 高乃荣 
单位:东南大学附属中大医院,普外科,江苏,南京,210009
关键词:BRAF基因 基因突变 消化道肿瘤 文献综述 
分类号:Q754, R735
出版年·卷·期(页码):2006·25·第三期(218-221)
摘要:

近年来,BRAF基因在肿瘤中的作用越来越受到重视.BRAF基因编码一种丝/苏氨酸特异性激酶(a serine/theronine-specific kinases),是RAS/RAF/MEK/ERK/MAPK通路(MEK:mitogen/extracellular signalregulated kinase;ERK:extracellular signal-regulated kinase;MAPK:mitogen-activated protein kinase)重要的转导因子,参与调控细胞内多种生物学事件,如细胞生长、分化和凋亡等[1].

参考文献:

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