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Amifostine在肿瘤化疗中作用的研究进展
作者:王根菊1 韩国荣2 
单位:1.东南大学,临床医学院,江苏,南京,210009; 2.东南大学附属南京第二医院,妇产科,江苏,南京,210009
关键词:氨磷汀 细胞保护剂 肿瘤 化学治疗 综述 
分类号:R453.9
出版年·卷·期(页码):2006·25·第二期(139-142)
摘要:

多年以来,人们一直在探索如何避免和减轻因肿瘤治疗而导致的对正常组织的毒副作用,借以提高放疗和化疗的效果来更加有效地治疗肿瘤病人.

参考文献:

[1] BRIZEL D M, OVERGAARD J. Dose amifostine have a role in chemoradiation treatment-, 2003(6)
[2] ANNE P R, CURRAN W J Jr. A phase Ⅱ trial of subcutaneous amifostine and radiation therapy in patients with head and neck cancer, 2002(zk)
[3] CULY C R, SPENDER C M. Amifostine an update on its clinical status as a cytoprotectant in patients with cacer recieving chemotherapy on radiotherapy and its potential therapentic application in myelodysplastic syndrom. 2001(5). doi:10.2165/00003495-200161050-00012
[4] 黄平, 丁惠萍. 氨磷汀. 中国肿瘤2000(10)
[5] 高怡瑾. 化/放疗患者的细胞保护剂--氨磷汀, 2000(5)
[6] ACOSTA J C, RICHARD C, DELGADO M D. Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells, 2003(9)
[7] LEE E J, GERHOLD M, PALMER M W. P53 protein regulates the effects of amifostine on apoptosis,cell cycle progression,and cytoprotection, 2003(5)
[8] KATAOKA Y, MURLEY J S, KHODAREV N N. Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine, 2002(1)
[9] GRDINA D J, MURLEY J S, KATAOKA Y E. Delationslips between cytoprotection and mutation prevention by WR-1065, 2002(92)
[10] KINTZEL P E. Anticancer drug-induced kiney disorders. 2001(1). doi:10.2165/00002018-200124010-00003
[11] 方志伟, 施学东, 魏广奇. 骨软组织恶性肿瘤患者大剂量顺铂、甲氨蝶呤化疗的肾损害, 1998(3)
[12] CHAUNCEY T R, GOOLEY T A, LIOID M E. Pilot trial of cytoprotection with amifostine given with high-dose chemotherapy and autologous peripheral blood stem cell trasplantation. 2000(4)
[13] 崔慧娟, 张树军, 李佩文. 阿米福汀保护肾脏的疗效观察. 中华肿瘤杂志2002(1)
[14] LORUSSO D, FERRANDINA G, GREGGI S. Phase Ⅲ multicenter randomized trial of amifostine as cytoprotectant in first-line chemotherapy in ovarian cancer patients. 2003(7). doi:10.1093/annonc/mdg301
[15] 申戈, 鲍云华. 防治癌症病人化疗毒性的临床研究及临床前研究. 国外医学(药学分册)1999(6)
[16] NAZEYROLLAS P, FRANCES C, PREVOST A. Efficiency of amifostine as a protection against doxorubicin toxicity in rats during a 12-day treatment. 2003(1A)
[17] LLLIANO A, BARLETTA E, DEMARINO V. New triplet chemotherapy combination with carboplatin,paclitaxel and gemcitabine plus amifostine support in advanced non small cell lung can-cer:a phase Ⅱ study. 2000(5C)
[18] IATROMANOLAKI A, SIVRIDIS E, MALTEZOS E. Down-regulation of intestinal-type alkaline phosphatase in the tumor vasculature and stroma provides a strong basis for explaining amifostine selectivity. 2002(zk). doi:10.1053/sonc.2002.37356
[19] LES F J, SHI G G, CORTES J E. Amifostine does not reduce the toxicity of the fludarabine and cyclophosphamide regimen in patients with chronic lymphocytic leukemia. 2003(3). doi:10.1007/s00280-003-0654-4
[20] 杨莉, 耿保琴. 细胞保护剂氨磷汀. 实用肿瘤杂志2001(3). doi:10.3969/j.issn.1001-1692.2001.03.032
[21] MOORE D H, DONNELLY J, MCGUIRE W P. Limited access trial using amifostine for protection against cisplatin-and three-hour paclitaxel-induced neurotoxicity:a phase Ⅱ study of the Gynecologic Oncology Group. 2003(22). doi:10.1200/JCO.2003.02.086
[22] HAIGENTZM J R, KIM M, SORICH J. Sewa phase I study of amifostine as a cytoprotector of the gemcitabine/cisplatin combination in patients with advanced solid malignancies. 2003(4). doi:10.1097/00001813-200304000-00010
[23] STANKIEWICZ A, SKRZYDLEWSKA E, MAKIELA M. Effects of amifostine on liver oxidative stress caused by cyclophosphamide administration to rats. 2002(2)
[24] BENNETT C L, LANE D, STINSON T. Economic analysis of amifostine as adjunctive support for patients with advanced head and neck cancer:preliminary results from a randomized phase Ⅱ clinical trial from Germany. 2001(2)
[25] KRUSE J J, STROOTMAN E G, WONDERGEM J. Effects of amifostine on radiation-induced cardiac damage. 2003(1). doi:10.1080/0891060310002168
[26] ZACKRISSON A L, MALMSTROM H, PERTERSON C. No evidence that amifostine influences the plasma pharmacokinetics of topotecan in ovarian cancer patients. 2002(2)
[27] VAN-DEN-BRANDE J, NANNAN-PANDAY V R, HOEKMAN K. Pharmacologic study of paclitaxel administered with or without the cytoprotective agent amifostine,and given as a single agent or in combination with epirubicin and cisplatin in patients with advanced solid tumors, 2001
[28] ANNE P R, CURRAN W J Jr. A phase Ⅱ trial of subcutaneous amifostine and radiation therapy in patients with head and neck cancer, 2002(zk) 

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