肾脏集合管癌的诊断和鉴别诊断-东南大学学报医学版

肾脏集合管癌的诊断和鉴别诊断

单位：东南大学附属中大医院,病理科,江苏,南京,210009

分类号：R737.11

出版年·卷·期（页码）：2006·25·第二期（110-113）

摘要：

目的:探讨肾脏集合管癌的病理学特征、免疫表型和鉴别诊断.方法:应用常规病理、免疫组化方法观察1例肾脏集合管癌标本并复习相关文献.结果:肿瘤位于肾脏中央区的髓质,境界不清.组织学以不规则的管状和管状乳头状结构为主,伴炎症性促纤维组织增生性间质.免疫组化显示肿瘤细胞34βE12和vimentin 阳性,CD10阴性.结论:肾脏集合管癌是肾脏少见的恶性上皮性肿瘤,诊断及鉴别诊断主要依靠病理组织学和免疫组化检查.

Objective To explore the pathologic features,immunophenotype and differential diagnosis of carcinoma of the collecting ducts of Bellini.Methods A case of carcinoma of the collecting ducts of Bellini was studied with conventional histopathological,immunohistochemical stains and review of the literature.Results The tumour was located centrally in the medullary zone of the kidney with irregular borders.Histologic examination showed prominent irregular tubular and tubulopapillary structures with a inflammatory desmoplastic stroma.Immunohistochemically,the neoplastic cells were positive for 34βE12 and vimentin,but negative for CD10.Conclusion Carcinoma of the collecting ducts of Bellini is a rare malignant epithelial tumour.The diagnosis of carcinoma of the collecting ducts of Bellini mainly relies on histopathological and immunohistochemical findings.

参考文献：

[1] JOHN N E, GUIDO S, JONATHAN I E. World health organization classification of tumours.Pathology &amp, genetics,tumours of the urinary system and male genital organs, 2004
[2] KENNEDY S M, MERINO M J, LINEHAN W M. Collecting duct carcinoma of the kidney. 1990(4). doi:10.1016/0046-8177(90)90209-N
[3] MANCILLA-JIMENEZ R, STANLEY R J, BLATH R A. Papilly renal cell carcinoma:a clinical,radiologic,and pathologic study of 34 cases. 1976(5). doi:10.1002/1097-0142(197612)38:6&lt, 2469::AID-CNCR2820380636&gt, 3.0.CO, 2-R
[4] SRIGLEY J R, EBLE J N. Collecting duct carcinoma of kidney. 1998
[5] 史时芳, 任国平, 余心如. 肾集合管癌(附5例报告). 中华泌尿外科杂志1994(5)
[6] 徐勇, 畅继武, 张祖诏. 肾集合管癌1例报告. 中华泌尿外科杂志1997(8)
[7] 孔详田, 曾荔, 宓培. 肾集合管癌10例分析. 中华肿瘤杂志2001(2)
[8] 葛建荣, 任国平. 肾集合管癌临床病理分析. 临床与实验病理学杂志2003(4). doi:10.3969/j.issn.1001-7399.2003.04.011
[9] 毛玉萍, 印洪林, 张彤. 肾集合管癌3例临床病理分析. 诊断病理学杂志2004(4). doi:10.3969/j.issn.1007-8096.2004.04.004
[10] 朱艳红, 刘芳, 顾莹莹. 肾集合管癌1例报道及文献复习. 临床与实验病理学杂志2004(4). doi:10.3969/j.issn.1001-7399.2004.04.019
[11] MILOWSKY M I, ROSMARIN A, TICKOO S K. Active chemotherapy for collecting duct carcinoma of the kidney:a case report and review of the literature. 2002(1). doi:10.1002/cncr.10204
[12] ORSOLA A, TRIAS I, RAVENTS C. Renal collecting (Bellini) duct carcinoma displays similar characteristics to upper tract urothelial cell carcinoma. 2005(1). doi:10.1016/j.urology.2004.08.012

服务与反馈：

【文章下载】【发表评论】【查看评论】【加入收藏】

提示：您还未登录，请登录！点此登录