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血管内药物涂层支架制备及应用的研究进展
作者:赵苏苏1 张东生1 卢勤2 
单位:1.东南大学基础医学院,病理学与病理生理学系,江苏省生物材料和器件重点实验室,江苏,南京,210009; 2.东南大学附属中大医院,放射科,江苏,南京,210009
关键词:血管内支架 药物涂层 血管内再狭窄 综述 
分类号:R318.08
出版年·卷·期(页码):2007·26·第五期(378-381)
摘要:

随着血管内支架植入术的广泛应用,由之而带来的支架植入术后血管再狭窄问题越来越受到人们的重视.研究表明,引起支架内再狭窄(ISR)的因素不尽相同,如血管内膜损伤、血栓形成、支架邻近血管重塑、炎症、愈合、基因等,但是目前公认的ISR形成机制除血管壁在血管扩张后弹性回缩和血栓形成外,损伤所诱导的血管平滑肌细胞(VSMC)过度增殖并向内膜迁移起关键作用[1].

参考文献:

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