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原发性高血压病患者颈动脉粥样硬化与血尿酸及超敏C反应蛋白的关系
作者:王颖捷1 程宇星2 
单位:1.南京大学医学院附属鼓楼医院,江苏南京,210008; 2.广州中医药大学第一附属医院,广东广州,510405
关键词:高血压 动脉粥样硬化 血尿酸 超敏C反应蛋白 
分类号:R544.1, R543.5
出版年·卷·期(页码):2008·27·第五期(354-356)
摘要:

目的:比较不同程度颈动脉粥样硬化与血尿酸及超敏C反应蛋白的关系,观察血尿酸与超敏C反应蛋白二者的相关性.方法:利用彩色多普勒超声检查将150例原发性高血压患者按颈动脉硬化程度分为颈动脉正常组、颈动脉内膜增厚组和颈动脉斑块形成组,分别测定各组血尿酸及超敏C反应蛋白的浓度,观察颈动脉粥样硬化程度与血尿酸及超敏C反应蛋白的关系.结果:各组的血尿酸及超敏 C反应蛋白的浓度差异有统计学意义(均P<0.05).超敏C反应蛋白与血尿酸浓度呈正相关.结论:血尿酸及超敏C反应蛋白的浓度与原发性高血压病患者的颈动脉粥样硬化程度有关.

Objective To study the relations of different degrees of carotid atheroscleorsis with blood uric acid(BUA) and high sensitive C-reactive protein(hsCRP) in patients with hypertension and to observe the correlation between BUA and hsCRP.Methods 150 patients with hypertension were divided into normal carotid group,carotid endometrial hyperplasia group and carotid plaques formation group depending on the scleorsis degree of their carotid by using color Doppler ultrasonography.The levels of their BUA,hsCRP were determined and the relations of carotid scleratheroma degree with hsCRP and BUA were observed.Results The differences of levels of BUA and hsCRP in kinds of groups had statistical significance,and correlation between hsCRP and BUA was positive.Conclusion The levels of BUA and hsCRP have certain relations with the degrees of carotid atheroscleorsis.

参考文献:

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