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离体犬前列腺微波凝固的实验研究
作者：王颖1 张炽敏2 李嘉2 李岭2 苏俊2 王玲2 
单位：1.东南大学,临床医学院,江苏,南京,210009； 2.东南大学附属中大医院,超声科,江苏,南京,210009
关键词：离体犬前列腺 经尿道微波凝固 前列腺增生症 
分类号：R-33, R454.1, R697.3
出版年·卷·期（页码）：2008·27·第三期（216-219）
摘要：

目的:探讨超声引导下经尿道微波凝固治疗前列腺病变的可行性.方法:25个离体犬前列腺进行经尿道微波凝固,能量分别为30W/120s、30W/180s、45W/60s、45W/120s及45W/180s,观察凝固灶的大小、形状,根据凝固灶的大小选择出适合于犬前列腺的最佳功率时间组合(为30W/180s);在这一功率时间组合下对54个离体犬前列腺进行324个点次的实际测温,分析其热场分布的特点.结果:30W/180s为本实验离体犬前列腺微波凝固治疗的最佳功率时间组合,凝固灶形态呈椭球形,温度场分布遵循由中央向周围递减的规律.结论:超声引导下经尿道微波凝固离体犬前列腺的方法为微波凝固治疗前列腺增生癌提供了实验基础.

Objective To investigate the feasibility of using transurethral microwave coagulation under ultrasound guidance in treating prostatic disease.Methods In vitro twenty-five canine prostates were coagulated with microwave energy for 120,180 s at 30W and 60,120,180 s at 45 W.The size and shape of coagulated area were observed and the optimum power and time(at 180 s and 30 W) were chosen according to the size of coagulated area;Real temperature was measured in 54 in vitro canine prostate for 324 times,then thermal distribution was analyzed at 180 s and 30 W.Results 180 s and 30 W were found to be the best applied in vitro canine prostate in this experiment.The shape of coagulated area was ellipsoid and the temperature decreased progressively from the center to the surrounding.Conclusion Microwave is feasible to coagulate in vitro canine prostate,which also provide a reliable experimental basis for the treatment of benign prostatic hyperplasia.
参考文献：

[1] SHAPIRO E, BECICH J I U, HARTANTO V. The relative promportion of stromal and epithelia hyperplasia is related to the development of symptomatic benign prostatic hyperplasia, 1992(5)
[2] CARIOU G, VUONG-NGNG P, MERRAN S. Correlations between radiography,ultrasonography,computed tomography and pathologic findings in prostatic disease. 1985(6). doi:10.1016/0090-4295(85)90375-9
[3] SHWAN A, BRONAGH L, JOHN D. Emerging minimally invasive techniques for treating localized prostate cancer, 2005(5)
[4] TUNUGUNTLA H S G R, EVANS C P. Minimally invasive therapies for benign prostatic hyperplasia. 2002(6)
[5] NASPRO R, SALONIA A, COLOMBO R. Update of the minimally invasive therapies for benign prostatic hyperplasia. 2005(1). doi:10.1097/00042307-200501000-00012
[6] MATTIAS W, BOB D. Transurethral microwave thermotherapy for treatment of benign prostatic hyperplasia, 2004(2-3)
[7] WALMSLEY K, KAPLAN S A. Transurethral microwave thermotherapy for benign prostate hyperplasia:separating truth from marketing type. 2004(4). doi:10.1097/01.ju.0000129967.30558.ca
[8] LIANG P, DONG B W, YU X L. Computed-aided dynamic simulation of miacrowave induced thermal distribution in coagulation of liver cancer. 2001(7). doi:10.1109/10.930907
[9] 梁萍, 董宝玮, 于晓玲. 超声引导下植入式微波热场在体模中的研究. 中华超声影像学杂志2002(4)
[10] CHRISTIAN H, MAGNUS B, THAYNE L. Evaluation of microwave thermotherapy with histopathology,magnetic resonance imaging and temperature mapping. 2004(2). doi:10.1097/01.ju.0000108136.41620.95
[11] GREGORY T, MARTIN M G, ERNEST G. The model of the local microwave hyperthemia treatment of benign prostatic hyperplasia. 1992(8). doi:10.1109/10.148391
[12] 王剑翔, 张炽敏. 肝脏肿瘤介入物理消融治疗. 东南大学学报(医学版)2004(5). doi:10.3969/j.issn.1671-6264.2004.05.021
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