Objective: To observe the analgesic effect of preoperative intravenous flurbiprofen combined lidocaine local infiltration anesthesia in the skeletal traction. Methods: Twenty-four patients who underwent a femoral supracondylar skeletal traction or tibial tubercular skeletal traction were randomized into two groups(12 patients in each). Lidocaine Group received intravenously fat emulsion injection 100 ml at 30 min before skeletal traction, and combined anaetheia group received intravenously 50 mg flurbiprofen (100 ml) at 30 min before skeletal traction. Postoperative analgesia was supplied with intramuscular 50 mg pethidine according to the patient's demand. Visual analog scale (VAS) score at preoperation, operation time, postoperation were measured and the earliest time of postoperative analgesic and amount of analgesics in 24 h after the operation were recorded. Results: VAS in combined anaetheia group was significantly lower than that in Lidocaine group during the intraoperative and postoperative time(all P<0.01). The amount of pethidine consumption in combined anaetheia group was also significantly (P=0.035) less than that in Lidocaine group within the first 24 h postoperatively. The earliest time of postoperative analgesic in combined anaetheia group was(16.75±2.19) h, and longer than that in Lidocaine group[(8.97±2.24) h].Amount of analgesics in 24 h after the operation was significantly reduced (P=0.003). Conclusion: Preoperative intravenous flubiprofen combined local infiltration anesthesia can effectively reduce the patients' pain within the intraoperative and postoperative time,and reduce the amount of opioid analgesics consumption.