独立成分分析观察不同性别正常人静息态听觉网络差异-东南大学学报医学版

独立成分分析观察不同性别正常人静息态听觉网络差异

单位：1. 东南大学医学院, 江苏南京 210009;
2. 东南大学附属中大医院放射科, 江苏南京 210009

分类号：R338.3;R445.2

出版年·卷·期（页码）：2013·32·第三期（279-283）

摘要：

目的:应用独立成分分析方法观察正常人不同性别间静息态听觉网络的差异。方法:将40名健康受试者按照性别分为两组,采用独立成分分析方法提取每组受试者的静息态听觉网络,并进一步进行两组间分析。结果:两组受试者的静息态听觉网络包括双侧颞叶、岛叶及扣带回,不同性别之间静息态听觉网络的差异脑区主要包括左侧额中下回、左侧海马区及右侧颞上回。结论:独立成分分析法可满意观察静息态听觉皮层网络,正常人不同性别之间听觉网络差异可能与不同性别对周围环境的感知差异相关。

Objective: Using independent components analysis to observe the gender-related difference between male and female auditory functional network.Methods: 40 healthy subjects were divided into two groups depending on their gender,independent components analysis was used to extract the resting-state auditory network of each group,then statistical analysis between groups was performed. Results: The resting-state auditory network of each group contained bilateral temporal lobe,insula and cingulate gyrus,the different brain areas between groups were found in left medial/inferior frontal gyrus,left hippocampus and right superior temporal gyrus. Conclusion: Resting-state auditory functional network can be satisfactorily acquired using independent components analysis,the difference of auditory network may correlated with the perception difference of environment between genders.

参考文献：

[1] HALL D A,HAGGARD M P,AKEROYD M A,et al."Sparse" temporal sampling in auditory fMRI[J].Hum Brain Mapp,1999,7(3):213-223.
[2] HINE J,THORNTON R,DAVIS A,et al.Does long-term unilateral deafness change auditory evoked potential asymmetries？[J].Clin Neurophysiol,2008,119(3):576-586.
[3] CHEN H,YAO D,ZHUO Y,et al.Analysis of fMRI data by blind separation of data in a tiny spatial domain into independent temporal component[J].Brain Topogr,2003,15(4):223-232.
[4] PEELLE J E,TROIANI V,GROSSMAN M,et al.Hearing loss in older adults affects neural systems supporting speech comprehension[J].J Neurosci,2011,31(35):12638-12643.
[5] de LUCA M,BECKMANN C F,de STEFANO N,et al.fMRI resting state networks define distinct modes of long-distance interactions in the human brain[J].Neuroimage,2006,29(4):1359-1367.
[6] 董国珍,杨志,王培培,等.利用独立成分分析技术和静息fMRI数据对脑功能区进行定位[J].中国医学影像技术,2008,24(11):1829-1832.
[7] 李晶,杨明,刘斌,等.静息态功能磁共振成像观察正常人听觉皮层功能[J].中国医学影像技术,2012,24(8):431-434.
[8] PHILLIPS M D,LOWE M J,LURITO J T,et al.Temporal lobe activation demonstrates sex-based differences during passive listening[J].Radiology,2001,220(1):202-207.
[9] RAMMSAYER T H,TROCHE S J.On sex-related differences in auditory and visual sensory functioning[J].Arch Sex Behav,2012,41(3):583-590.
[10] TEKI S,KUMAR S,von KRIEGSTEIN K,et al.Navigating the auditory scene:an expert role for the hippocampus[J].J Neurosci,2012,32(35):12251-12257.
[11] 朱新,黄志纯,刘斌,等.听觉皮层网络老化的静息态功能磁共振成像研究[J].东南大学学报:医学版,2012,31(5):577-581.

服务与反馈：

【文章下载】【发表评论】【查看评论】【加入收藏】

提示：您还未登录，请登录！点此登录