[1] 王中兴,鹿均先,熊传芝.人脂肪干细胞体外培养及向软骨细胞诱导分化的实验研究[J].东南大学学报:医学版,2009,28(2):126-130.
[2] MARKLEIN R A,BURDICK J A.Controlling stem cell fate with material design[J].Adv Mater,2010,22:175-189.
[3] VOYTIK-HARBIN S L.Three-dimensional extracellular matrix substrates for cell culture[J].Methods Cell Biol,2001,63:561-581.
[4] NILSANG S,NEHRU V,PLIEVA F M,et al.Three-dimensional culture for monoclonalantibody production by hybridoma cells immobilized in macroporous gel particles[J].Biotechnol Prog,2008,24(5):1122-1131.
[5] 徐飞,王大伟,陈双峰.电纺PLLA/PVP纳米纤维膜材料用于血管组织工程的前期研究[J].东南大学学报:医学版,2011,30(3):391-401.
[6] KAUSHAL S,AMIEL G E,GULESERIAN K J,et al.Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo[J].Nat Med,2001,7(9):1035-1040.
[7] MCNAUGHT A D,WILKINSON A.IUPAC Compendium of Chemical Terminology.2nd Edition.Oxford:Blackwell Scientific Publications,1997:927.
[8] Van WEZEL A L.Growth of cell-strains and primary cells on micro-carriers in homogeneous culture[J].Nature,1967,216(5110):64-65.
[9] THISSEN H,CHANG K Y,TEBB T A,et al.Synthetic biodegradable microparticles for articular cartilage tissue engineering[J].J Biomed Mater Res Part A,2006,77A(3):590-598.
[10] MALDA J,FRONDOZA C G.Microcarriers in the engineering of cartilage and bone[J].Trends Biotechnol,2006,24(7):299-304.
[11] HONG Y,GAO C Y,XIE Y,et al.Collagen-coated polylactide microspheres as chondrocyte microcarriers[J].Biomaterials,2005,26(32):6305-6313.
[12] KATO D,TAKEUCHI M,SAKURAI T,et al.The design of polymer microcarrier surfaces for enhanced cell growth[J].Biomaterials,2003,24(23):4253-4264.
[13] MALDA J,KREIJVELD E,TEMENOFF J S,et al.Expansion of human nasal chondrocytes on macroporous microcarriers enhances redifferentiation[J].Biomaterials,2003,24(28):5153-5161.
[14] KIM H W,GU H J,LEE H H.Microspheres of collagen-apatite nanocomposites with osteogenic potential for tissue engineering[J].Tissue Eng,2007,13(5):965-973.
[15] MELERO-MARTIN J M,DOWLING M A,SMITH M,et al.Expansion of chondroprogenitor cells on macroporous microcarriers as an alternative to conventional monolayer systems[J].Biomaterials,2006,27(15):2970-2979.
[16] MALDA J,FRONDOZA C G.Microcarriers in the engineering of cartilage and bone[J].Trends Biotechnol,2006,24(7):299-304.
[17] 刘国诠.生物工程下游技术[M].北京:化学工业出版社,2003.
[18] GOKMEN M T,DU PREZ F E.Porous polymer particles-A comprehensive guide to synthesis,characterization,functionalization and application[J].Prog Polym Sci,2012,37(3):365-405.
[19] KIM T K,YOON J J,LEE D S,et al.Gas foamed open porous biodegradable polymeric microspheres[J].Biomaterials,2006,27:152-159.
[20] SAHOO S K,PANDA A K,LABHASETWAR V.Characterization of porous PLGA/PLA microparticles as a scaffold for three dimensional growth of breast cancer cells[J]. Biomacromolecules,2005,6:1132-1139.
[21] NAIDOO K,ROLFES H,EASTON K,et al.An emulsion preparation for novel micro-porous polymeric hemi-shells[J].Mater Lett,2008,62:252-254.
[22] SHI X D,SUN L,JIANG J,et al.Biodegradable polymeric microcarriers with controllable porous structure for tissue engineering[J].Macromol Biosci,2009,9:1211-1218.
[23] STRAUB J A,CHICKERING D E,CHURCH C C,et al.Porous PLGA micropaticles:AI-700,an intravenously administered ultrasound contrast agent for use in echocardiography[J].J Control Release,2005,108(1):21-32.
[24] NIHANT N,GRANDFILS C.Microencapsulation by coacervation of poly(lactide-co-glycolide) IV. Effect of the processing parameters on coacervation and encapsulation[J].J Control Release,1995,35(2):117-125.
[25] YODTHONG B.Porous microspheres of methoxy poly(ethylene glycol)-b-poly(ε-caprolactoneco -D,L-lactide) prepared by a melt dispersion method [J].Polymer,2009,50:4761-4767.
[26] MANKANI M H,KUZNETSOV S A,FOWLER B,et al.In vivo bone formation by human bone marrow stromal cells:Effect of carrier particle size and shape[J].Biotechnol Bioeng,2001,72(1):96-107.
[27] QIU Q Q,DUCHEYNE P,AYYASWAMY P S.Fabrication,characterization and evaluation of bioceramic hollow microspheres used as microcarriers for 3-D bone tissue formation in rotating bioreactors[J].Biomaterials,1999,20(11):989-1001.
[28] SUTHERLAND R M.Cell and environment interactions in tumor microregions:the multicell spheroid model[J].Science,1988,240:177-184.
[29] 王佃亮,肖成祖.动物细胞高密度培养用多孔微球[J].生物工程进展,1998,18(2):46-49.
[30] WEBB K,HLADY V,TRESCO P A.Relative importance of surface wettability and charged functional groups on NIH 3T3 fibroblast attachment,spreading,and cytoskeletal organization[J].Biomed Mater Res,1998,41(3):422-430.
[31] TZIAMPAZIS E,KOHN J,MOGHE P V.PEG-variant biomaterials as selectively adhesive protein templates:model surfaces for controlled cell adhesion and migration[J]. Biomaterials,2000,21(5):511-520.
[32] LEE J H,KHANG G,LEE J W,et al.Platelet adhesion onto chargeable functional group gradient surfaces[J].Biomed Mater Res,1998,40(2):180-186.
[33] BALDWIN S P,SALTZMAN W M.Polymers for tissue engineering[J].Trends Polym Sci,1996,4(6):177-182.
[34] HONG Y,GAO C Y,XIE Y,et al.Collagen-coated polylactide microspheres as chondrocyte microcarriers[J].Biomaterials,2005,26(32):6305-6313.
[35] KIM H W,GU H J,LEE H H.Microspheres of collagen-apatite nanocomposites with osteogenic potential for tissue engineering[J].Tissue Eng,2007,13(5):965-973.
[36] GARKHAL K,VERMA S,TIKOO K,et al.Surface modified poly(L-lactide-co-epsilon-caprolactone) microspheres as scaffold for tissue engineering[J].J Biomed Mater Res Part A,2007,82A(3):747-756.
[37] HERSEL U,DAHMEN C,KESSLER H.RGD modified polymers:biomaterials for stimulated cell adhesion and beyond[J].Biomaterials,2003,24(24):4385-4415.
[38] SINGHVI R,KUMAR A,LOPEZ G P,et al.Enginerring cell shape and function[J]. Science,1994,264:696-698.
[39] NOJEHDEHIANA H,MOZTARZADEH F,BAHARVAND H.Preparation and surface characterization of poly-l-lysine-coated PLGA microsphere scaffolds containing retinoic acid for nerve tissue engineering:in vitro study[J].Colloid Surf B-Biointerfaces,2009,73:23-29.
[40] NEWMAN K D,MCBURNEY M W.Poly(d,l lactic-co-glycolic acid) microspheres as biodegradable microcarriers for pluripotent stem cells[J].Biomaterials,2004,5:5763-5771.
[41] HYNES R O.Integrins:bidirectional,allosteric signaling machines[J].Cell,2002,110(6):673-687.
[42] HERSEL U,DAHMEN C,KESSLER H.RGD modied polymers:biomaterials for stimulated cell adhesion and beyond[J].Biomaterials,2003,24:4385-4415.
[43] CHEN R,CURRAN S J,CURRAN J M.The use of poly(L-lactide) and RGD modied microspheres as cellcarriers in a ow intermittency bioreactor for tissue engineering cartilage[J].Biomaterials,2006,27:4453-4460. |
