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功能化葡聚糖用于三维细胞培养及发展前景
作者:朱长皓  张天柱  胡克  张启英  郭兆彬  顾宁 
单位:东南大学生物科学与医学工程学院, 江苏省生物材料与器件重点实验室, 江苏 南京 210009
关键词:三维细胞培养 功能化葡聚糖 发展前景 文献综述 
分类号:Q813.11
出版年·卷·期(页码):2013·32·第一期(80-84)
摘要:

传统的在二维表面的细胞生长和操纵方法已经被证实在细胞生物学、生物化学和药物检测方面存在不足。随着材料化学、材料制造和加工技术的进步,使得三维细胞培养基质的设计具有更好的几何尺寸、化学性质和天然细胞外基质的信号环境。在本文中,我们研究了目前三维细胞培养基质的现状,并从材料性能、制造、功能方面进行分析,特别强调的是葡聚糖材料用于三维细胞培养,介绍了多种改性葡聚糖三维细胞培养基质。最后概述了这一领域面临的挑战和未来几年的发展前景。

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