生殖器疱疹患者合并TP、HIV、HCV感染状况分析-东南大学学报医学版

生殖器疱疹患者合并TP、HIV、HCV感染状况分析

单位：南京市CDC皮肤病性病专科医院

分类号：

出版年·卷·期（页码）：2012·31·第五期（607-609）

摘要：

通过对本院性病门诊诊断为生殖器疱疹（Genital Herpes，GH）的213例患者和临床排除GH的427例患者均进行梅毒螺旋体明胶凝集（Treponema pallidum particle agglutination test，TPPA）,HIV、HCV抗体的检测，以了解GH人群与梅毒螺旋体(Treponema Pallidum，TP)、HIV、HCV的相关性，为性病门诊制订性病防控措施提供科学依据。方法：对所研究对象抽血并分离血清，用梅毒螺旋体明胶凝集试验(TPPA)检测梅毒特异性抗体（简称TPPA抗体试验），用ELISA法检测HCV抗体、HIV抗体，并用免疫印迹（Weston Blot，WB）对HIV抗体进行确认。结果：GH患者组，TPPA阳性率为31.03%，HIV抗体阳性率为4.14%，HCV抗体阳性率为5.52%；非GH患者组，TPPA、HIV、HCV抗体阳性率分别为3.39%，0.34%和0.68%。结论：GH患者组TPPA、HIV、HCV抗体阳性率明显高于非GH患者组，对GH患者应加强干预，以进一步控制梅毒螺旋体、HIV、HCV的传播。

Objective:To investigate the relationship of Genital Herpes (GH）and Treponema pallidum(Treponema Pallidum,TP),HIV,HCV , and to provide a scientific basis of prevention and control measures for STD clinic.We analyzed the diagnosis rate of GH and GH co-infection with Treponema pallidum,HIV and HCV in first-visit patients with STD. Methods: 640 blood samples derived from first-visit patients with STD were tested for Treponema pallidum,HIV and HCV serum antibodies.Results:was 32.95%. Diagnosis rate was 37.12% and 26.70% in males and females respectively.Among patients with GH,the infection rate was 31.03% for Treponema pallidum,4.14% for HIV and 5.52% for HCV.Among patients for not GH group,the infection rate of HIV,HCV and Treponema pallidum was 3.39%,0.34% and 0.68% respectively.Conclusion:The infection rate of Treponema pallidum,HIV and HCV had a significant increase in patients with GH. Thus,the patients with GH should be protected from co-infection with syphilis, HIV and HCV transmission.

参考文献：

服务与反馈：

【文章下载】【发表评论】【查看评论】【加入收藏】

提示：您还未登录，请登录！点此登录