[Abstract] Objective: The purpose of this investigation was to analyze and probe into correlation of mental symptoms in SCL-90 and neurobehavioral functions in neurobehavioural core test battery(NCTB). Method: SCL-90 and The neurobehavioral core test battery (NCTB) were detected and analyzed on 87 train conductors selected according to the random cluster sampling method in passenger depot of Jinan Railway Administration. Results: There was positive correlation between nine factors (somatization, obsessive-compulsive, interpersonal- sensitivity, depression, anxiety, hostility, phobicanxiety, paranoidideation and psychotism) of SCL-90 and five negative mood factors (tension-anxiety, depression-dejection, anger-hostility, fatigue-inertia and confusion-bewiderment) of POMS (p＜0.05). There was negative correlation between three factors (somatization, obsessive-compulsive and anxiety) of SCL-90 and two test scores (Benton visual retention test and digit symbol test) of NCTB (p＜0.05). There was negative correlation between three factors (tension-anxiety, depression-dejection and anger-hostility) of POMS and two test scores (average reaction time and the slowest simple reaction time) of NCTB (p＜0.05). There was negative correlation between five factors (tension-anxiety, depression-dejection, anger-hostility, fatigue-inertia and confusion-bewiderment) of POMS and two test scores (digit symbol test and total tapping) of NCTB (p＜0.05). Conclusion: The results suggested that there was preferable correlation between nine factors of SCL-90 and neurobehavioral functions. The laboureres’ health affected by occupational stress could be completely evaluated by means of SCL-90 combining NCTB.