目的:了解生殖器疱疹(genital herpes, GH)患者的梅毒螺旋体(treponema pallidum, TP)、艾滋病病毒(human immunodeficiency virus, HIV)、丙型肝炎病毒(hepatitis C virus, HCV)抗体水平,为性病门诊制订性病防控措施提供科学依据。方法:对所研究对象抽血并分离血清,用梅毒螺旋体明胶凝集试验(TPPA)检测梅毒特异性抗体,用ELISA法检测HCV抗体、HIV抗体,并用蛋白质印迹法对HIV抗体进行确认。结果:GH患者组TPPA阳性率为30.99%,HIV抗体阳性率为4.23%,HCV抗体阳性率为5.63%,均高于非GH患者组(分别为χ2=99.75,P=0.000;χ2=14.72,P=0.000;χ2=9.30,P=0.002)。结论:GH患者组TPPA、HIV、HCV抗体阳性率明显高于非GH患者组,对GH患者应加强干预,以进一步控制TP、HIV、HCV的传播。 |
Objective: To investigate the antibody levels of treponema pallidum(TP), human immunodeficiency virus(HIV), hepatitis C virus(HCV) among simplex herpes(GH) patients. Methods: 640 blood samples derived from first-visit patients with sexually transmitted diseases were tested for TP, HIV and HCV serum antibodies. Results: GH diagnosis rate was 19.27% and 54.30% in males and females respectively. Among patients with GH, the infection rate was 30.99% for TP, 4.23% for HIV and 5.63% for HCV. Among patients without GH, the infection rate of HIV, HCV and TP was 3.38%, 0.23% and 1.41% respectively. Conclusion: The infection rate of TP, HIV and HCV had a significant increase in patients with GH. Thus, the patients with GH should be protected from co-infection with TP, HIV and HCV transmission. |
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