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男性高血压患者动态血压节律异常与良性前列腺增生的相关性研究
作者:马金宝  秦明照 
单位:首都医科大学附属北京同仁医院 干部医疗科,北京 100730
关键词:高血压 动态血压监测 昼夜节律 良性前列腺增生 
分类号:R544.1; R697.32
出版年·卷·期(页码):2012·31·第四期(453-455)
摘要:

目的:探讨男性高血压患者血压节律异常与良性前列腺增生间的相关性。方法:对198例(45~92岁)高血压合并良性前列性增生的患者进行24 h动态血压监测,根据夜间血压下降率分为杓型组(100例)和非杓型组(98例),比较两组患者低密度脂蛋白、糖化血红蛋白、踝臂指数、收缩压、舒张压、前列腺抗原及前列腺体积。结果:非杓型组和杓型组昼间收缩压[(130.2±9.4) mmHg vs(128.6±7.5) mmHg,(1 mmHg=0.133 kPa)]、昼间舒张压[(76.0±6.1) mmHg vs(75.8±5.5) mmHg]无明显差异,但夜间收缩压[(134.8±9.7) mmHg vs (115.6±3.0) mmHg]及夜间舒张压[(78.8±6.5) mmHg vs(67.5±2.7) mmHg]有显著性差异(P<0.05),非杓型组和杓型组患者前列腺体积有显著性差异[(44.8±11.6) ml vs(35.4±9.9) ml,P<0.05]。结论:血压患者血压节律异常与前列腺增生程度可能存在相关性。

Objective: To investigate the correlation between the circadian rhythm abnormality of blood pressure and benign prostatic hyperplasia in male patients with essential hypertension. Methods: One hundred and ninety-eight male hypertensive patients(aged 45 to 92 years) were included and divided into dipper group(100 patients) and non-dipper group(98 patients) according to the rate of decrease in nocturnal blood pressure by ambulatory blood pressure monitoring. LDL-C, GHb, ABI, SBP, DBP, prostatic antigen and prostatic volume were recorded. [JP2]Results: There were no statistical differences between non-dipper group and dipper group in day systolic blood pressure [(130.2±9.4) mmHg vs(128.6±7.5) mmHg] and day diastolic blood pressure [(76.0±6.1) mmHg vs(75.8±5.5) mmHg](P>0.05). Night systolic blood pressure [(134.8±9.7) mmHg vs(115.6±3.0) mmHg] and night diastolic blood pressure [(78.8±6.5) mmHg vs(67.5±2.7) mmHg] in non-dipper group were significantly higher than those in dipper group(P<0.05). Prostatic volume in non-dipper group were significantly higher than those in dipper group [(44.8±11.6) ml vs(35.4±9.9) ml]. Conclusions: The circadian rhythm abnormality of blood pressure in patients with essential hypertension may be associated with the degree of prostatic hyperplasia.

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