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子宫肌瘤发病的相关危险因素Logistic回归分析
作者:张兰1  余进进2 
单位:1. 无锡市第一中学 医务室, 江苏 无锡 214031;
2. 无锡市第四人民医院 妇产科, 江苏 无锡 214062
关键词:子宫肌瘤 Logistic回归 危险因素 
分类号:R737.33; R73-31
出版年·卷·期(页码):2012·31·第二期(213-216)
摘要:

目的:研究子宫肌瘤发病的相关危险因素,为其预防提供理论依据。方法:对2008年5月至2011年5月我校健康体检发现的子宫肌瘤患者102例的临床资料采用1∶1病例对照研究进行调查,并采用SPSS 11.5软件进行多因素非条件Logistic回归模型分析子宫肌瘤发病的相关危险因素。结果与结论:子宫肌瘤发病与月经紊乱、流产≥2次、阴道炎、盆腔炎、宫颈炎和亲属有子宫肌瘤史有关。

Objective: To analyse the risk factors of uterine myoma, and provide the theory basis for prevention of uterine myoma. Methods: The clinical data of 102 cases with uterine myoma found in health examination from May, 2008 to May, 2011 were analysed by 1∶1 matched case-control study. The risk factors of uterine fibroids were analysed by many factors unconditional Logistic regression model. Results and Conclusion: Disorders of menstruation, abortion more than 2 times, vaginitis, cervicitis, pelvic inflammatory disease, relatives of uterine fibroids history correlate with the uterine leiomyoma.

参考文献:

[1] van VOORHIS B.A 41-year-old woman with menorrhagia,anemia,and fibroids:review of treatment of uterine fibroids[J].JAMA,2009,301(1):82-93.
[2] LERNER D,MIRZA F G,CHANG H,et al.Impaired work performance among women with symptomatic uterine fibroids[J].J Occup Environ Med,2008,50(10):1149-1157.
[3] 王瑾蔚,蒋树娟,张羽.雌、孕激素受体在子宫肌瘤、子宫腺肌病中的表达及其意义[J].现代医学,2009,37(4):268-270.
[4] 任慕兰,陈锡玲.米非司酮对子宫肌瘤培养细胞雌、孕激素受体和表皮生长因子受体表达的影响[J].东南大学学报:医学版,2004,23(6):370-372.
[5] BEN-NAGI J,MIELL J,MAVRELOS D,et.al.Endometrial implantation factors in women with submucous uterine fibroids[J].Reprod Biomed Online,2010,21(5):610-615.
[6] STEWART L,GLENN G M,STRATTON P,et al.Association of germline mutations in the fumarate hydratase gene and uterine fibroids inwomen with hereditary leiomyomatosis and renal cell cancer[J].Arch Dermatol,2008,144(12):1584-1592.

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