Objective: To investigate the applications of gastroscope in the diagnosis and surgical treatment of anastomotic hemorrage after esophago-gastrostomy. Methods: A group of 9 patients suffered from anastomotic haemorrhage after esophago-gastrostomy was analyzed retrospectively. Intensive suturation of the stoma was used in 4 cases which were detected in operation. Injecting adrenalin in multi-locations around the bleeding place was used in one patient. The other 4 cases were cured with gastroscope associated re-operation. Results: All of the 9 patients were healed and one patient developed to anastomotic stenosis, 3 cases suffered from pulmonary infections which were cured by antibiotics. No re-haemorrhage, anastomotic leakage and other severe complications developed. Conclusion: Gastroscope should be the first diagnostic and curative option of anastomotic haemorrage after esophago-gastrostomy. Gastroscope associated re-operation is safe and available treatment and can diminish the damage of re-operation.