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MTSS1——候选的肿瘤转移抑制基因?
作者:张凤  樊红 
单位:东南大学 "发育与疾病相关基因"教育部重点实验室, 基础医学院 遗传与发育生物学系, 江苏 南京 210009
关键词:MTSS 1 MIM/MIM-B 肿瘤转移 抑制基因 细胞骨架 文献综述 
分类号:R73-37
出版年·卷·期(页码):2009·28·第三期(239-243)
摘要:
参考文献:

[1] 梁静.恶性肿瘤转移机制及分子基础[J].武警医学院学报,2003,13(1):53-56.
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[5] WOODINGS J A,SHARP S J,MANCHESKY L M.MIM-B,a putative metastasis suppressor protein,binds to actin and to protein tyrosine phosphatase δ[J].Biochem J,2003,371:463-471.
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[9] NIXDORF S,GRIMM M O,LOGERG R,et al.Expression and regulation of MIM (Missing in Metastasis),a novel putative metastasis suppressor gene,and MIM-B,in bladder cancer cell lines[J].Cancer Lett,2004,215:209-222.
[10] CALLAHAN C A,OFSTAD T,HORNG J K,et al.MIM/BEG4,a sonic hedgehog-responsive gene that potentiates Gli-dependent transcription[J].Genes Dev,2004,18:2724-2729.
[11] BAI C B,AUERBACH W,LEE J S,et al.Gli2,but not Gli1,is required for initial Shh signaling and ectopic activation of the Shh pathway[J].Development,2002,129:4753-4761.
[12] BAI C B,AUERBACH W,LEE J S,et al.Gli2,but not Gli1,is required for initial Shh signaling and ectopic activation of the Shh pathway[J].Development,2002,129:4753-4761.
[13] LOBERG R D,NEELEY C K,ADAM-DAY L L,et al.Differential expression analysis of MIM (MTSS1) splice variants and a functional role of MIM in prostate cancer cell biology[J].Int J Oncol,2005,26:1699-1705.
[14] BOMPARD G,SHARP S J,FREISS G,et al.Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B[J].J Cell Sci,2005,18:5393-5403.
[15] MATTILA P K,SALMINEN M,YAMASHIRO T,et al.Mouse MIM,a tissue-specific regulator of cytoskeletal dynamics,interacts with ATP actin monomers through its C-terminal WH2 domain[J].J Biol Chem,2003,278:8452-8459.
[16] UTIKAL J,GRATCHEV A,MULLER-MOLINET I,et al.The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation[J].Int J Cancer,2006,119:2287-2293.
[17] STEPHANIE M,GUAN X Y.Clinicopathological significance of missing in metastasis B expression in hepatocellular carcinoma[J].Human Pathology,2007,38:1201-1206.

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