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1例脂质沉积性肌病临床及病理分析
作者:郭怡菁1  卢万俊1  刘韶华1  张平2  周红1 
单位:1. 东南大学附属中大医院 神经内科, 江苏 南京 210009;
2. 南京医科大学第二附属医院 病理科, 江苏 南京 210011
关键词:脂质沉积性肌病 线粒体肌病 病例报告 
分类号:R746.9
出版年·卷·期(页码):2009·28·第二期(144-146)
摘要:

脂质沉积性肌病(LSM)是一种脂肪酸代谢障碍导致的肌病,1972年Engel首次报道,国内对该病的报道较少。LSM十分少见,与重症肌无力、进行性肌营养不良、多发性肌炎等鉴别困难,临床上误诊率非常高。作者就1例确诊LSM患者,详细阐明了该病临床及病理特点,以提高对该病的认识。

Lipid storage myopathy (LSM) is a type of myopathy induced by metabolic disturbance of fatty acid.In 1972,Engel firstly reported about this disease,however,it was rarely reported in our country.Since it is difficult to identify LSM from myasthenia gravis,progressive muscular dystrophy and multiple myositis,the clinical misdiagnosis rate of LSM is pretty high.In order to improve recognition of LSM,we discuss here about one patient with LSM with final diagnosis,to elucidate the clinical feature and pathological characteristic of LSM.

参考文献:

[1] 骆翔,姜亚平,唐荣华,等.脂质沉积性肌病1例报告及相关文献复习[J].脑与神经疾病杂志,2003,11(2):90.
[2] 严莉,鹏斌,陈琳,等.脂质沉积性肌病30例临床资料分析[J].中华神经科杂志,2005,38(8):507.
[3] MANNAN A A,RALTE A M,SHARMA M C,et al.Lipid storage myopathy[J].Indian J Pediatr,2004,71:277-278.
[4] TURNBULL D M,SHEPHERD I M,ASHWORTH B,et al.Lipid storage myopathy associated with low acyl-CoAdehydrogenase activiting[J].Brain,1988,111:815-828.
[5] 卢永昕.从心肌病的新观念看分子心脏病时代的来临[J].临床心血管病杂志,2006,22(7):385-387.
[6] 卫华,王玉平.脂质沉积性肌病[J].脑与神经疾病杂志,2005,13(2):141-142.
[7] VOCKLEY J,WHITEMAN D A.Defects of mitochondrial beta-oxidation:a growing group of disorders[J].Neuromuscul Disord, 2002,12(3):235.
[8] ARAKI E,KOBAYASHI T,KOHTAKE N,et al.A riboflavin-responsive lipid stoeage myopathy due to multiple acyl-coa dehydrogenase deficiency:an adult case[J].J Neurol Sci,1994,126(2):202.
[9] 王翠娣,殷剑,许贤豪.脂质沉积性肌病八例临床病理研究[J].中华病理学杂志,2001,30(1):19.

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