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乳腺癌新辅助化疗疗效的评估方法及其进展
作者:林嘉燕  张建国 
单位:哈尔滨医科大学附属第二医院 乳腺外科, 黑龙江 哈尔滨 150000
关键词:乳腺癌 新辅助化疗 疗效评价 综述 
分类号:R737.9
出版年·卷·期(页码):2019·38·第四期(727-731)
摘要:

乳腺癌新辅助化疗旨在争取晚期乳腺癌患者手术机会、提高保乳率和提升患者生存质量,被广泛应用于临床。更准确的疗效评价系统对于手术时机的选择和化疗方案的实施有重要的决策作用,一般的影像学技术易受主观因素影响且仅能体现宏观形态学的改变,病理学评价虽然是疗效评估的金标准但是存在结果延后性的缺点。本文作者详述各种评测方法在新辅助化疗过程中的实施原理和临床应用情况。

参考文献:

[1] TORRE L A,BRAY F,SIEGEL R L,et al.Global cancer statistics,2012[J].CA Cancer J Clin,2015,65(2):87-108.
[2] 陈万青,郑荣寿.中国女性乳腺癌发病死亡和生存状况[J].中国肿瘤临床,2015,42(13):668-674.
[3] SIMMONS C E,HOGEVEEN S,LEONARD R,et al.A Canadian national expert consensus on neoadjuvant therapy for breast cancer:linking practice to evidence and beyond[J].Curr Oncol,2015,22(Suppl 1):S43-53.
[4] GIANNI L,PIENKOWSKI T,YOUNG-HYUCKI M,et al.Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced,inflammatory,or early HER2-positive breast cancer (NeoSphere):a randomised multicentre,open-label,phase 2 trial[J].Lancet Oncol,2012,13(1):25-32.
[5] GIANNI L,EIERMANN W,SEMIGLAZOV V,et al.Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone,in patients with HER2-positive locally advanced breast cancer (the NOAH trial):a randomised controlled superiority trial with a parallel HER2-negative cohort[J].Lancet,2010,375(9712):277-384.
[6] HOLMES D,COLFRY A,CZERNIECKI B,et al.Performance and practice guideline for the use of neoadjuvant systemic therapy in the management of breast cancer[J].Ann Surg Oncol,2015,22(10):3184-3190.
[7] 周如海,邬颖杰,吴猛,等.超声造影技术在乳腺癌新辅助化疗疗效评估中的应用价值[J].医学影像学杂志,2015,25(3):711-714.
[8] 常立功,周齐.彩色多普勒超声联合MRI对小乳腺癌的诊断[J].现代医学,2015,43(12):1566-1568.
[9] ASANO Y,KASHIWAGI S,ONODA N,et al.Clinical verification of sensitivity to preoperative chemotherapy in cases of androgen receptor-expressing positive breast cancer[J].Br J Cancer,2016,114(1):14-20.
[10] BOWEN M E,MONE M C,BUYS S S,et al.Surgical outcomes for mastectomy patients receiving neoadjuvant chemotherapy:a propensity-matched analysis[J].Ann Surg,2017,265(3):448-456.
[11] 盛洁,高洁, 钱朋飞.X线钼靶与高频彩超对早期乳腺癌诊断的对比研究[J].中国临床医学影像杂志,2012,23(3):206-208.
[12] CASTANEDA C A,FLORES R,ROJAS K,et al.Association between mammographic features and response to neoadjuvant chemotherapy in locally advanced breast carcinoma[J].Hematol Oncol Stem Cell Ther,2014,7(4):149-156.
[13] CHEN J H,BAHRI S,MEHTA R S,et al.Impact of factors affecting the residual tumor size diagnosed by MRI following neoadjuvant chemotherapy in comparison to pathology[J].J Surg Oncol,2014,109(2):158-167.
[14] 顾雅佳,冯晓源,邱龙华,等.DWI对局部进展期乳腺癌新辅助化疗疗效评价的初步研究[J].放射学实践,2007,22(7):1249-1255.
[15] 吴延春,许新堂.联合钼靶X线摄影、MRI动态增强及弥散加权成像对乳腺癌的诊断价值[J].现代医学,2016,44(10):1327-1332.
[16] SHERI A,SMITH I E,JOHNSTON S R,et al.Residual proliferative cancer burden to predict long-term outcome following neoadjuvant chemotherapy[J].Ann Oncol,2015,26(1):75-80.
[17] BOSSUYT V,PROVENZANO E,SYMMANS W F,et al.Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration[J].Ann Oncol,2015,26(7):1280-1291.
[18] BASELGA J,BRADBURY I,EIDTMANN H,et al.Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO):a randomised, open-label,multicentre,phase 3 trial[J].Lancet,2012,379(9816):633-640.
[19] GERDES J,LEMKE H,BAISCH H,et al.Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67[J].Immunol,1984,133(4):1710-1715.
[20] DAWOOD S.Triple-negative breast cancer[J].Drugs,2010,70(17):2247-2258.
[21] HOSTER E,ROSENWALD A,BERGER F,et al.Prognostic value of Ki-67 index,cytology,and growth pattern in mantle-cell lymphoma:results from randomized trials of the European mantle cell lymphoma network[J].J Clin Oncol,2016,34(12):1386-1394.
[22] 桑果,王本忠.乳腺癌新辅助化疗不同方案近期疗效观察及化疗前后Ki-67的表达变化[J].安徽医科大学学报,2011,46(11):1181-1184.
[23] 杨芳,于雁.肿瘤微环境——肿瘤转移的关键因素[J].中国肺癌杂志,2015,18(1):48-54.
[24] 徐熠琳,李军楠,刘雪静,等.乳腺血氧功能成像技术与超声及X线检查联合应用诊断乳腺癌的价值[J].山东医药,2016,26(4):16-18.
[25] ZHONG X,XIE G,ZHANG Z,et al.MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy[J].Oncotarget,2016,7(38):61166-61182.
[26] DING M,SUN X,ZHONG J,et al.Decreased miR-200a-3p is a key regulator of renal carcinoma growth and migration by directly targeting CBL[J].J Cell Biochem,2018,119(12):9974-9985.
[27] 何春波,宿菲,齐秀英,等.血清miR_34a表达水平预测乳腺癌新辅助化疗疗效[J].解剖科学进展,2017,23(8):467-470,474.

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