直肠癌Dixon术后吻合口漏影响因素的分析-东南大学学报医学版

直肠癌Dixon术后吻合口漏影响因素的分析

单位：1. 南通大学医学院附属南京江北人民医院普外科, 江苏南京 210048;
2. 东南大学附属中大医院普外科, 江苏南京 210009

分类号：R619.9

出版年·卷·期（页码）：2017·36·第六期（958-961）

摘要：

目的：调查直肠癌Dixon术后吻合口漏的发生情况，研究其发生的影响因素。方法：搜集2005年1月至2015年8月因直肠癌行Dixon术的257例患者的临床资料，分析术后吻合口漏发生的影响因素。结果：257例行直肠癌Dixon术的患者中术后发生吻合口漏16例，发生率为6.23%。其中，肿瘤位于腹膜返折以上和以下吻合口漏的发生率分别为0和8.89%（P=0.016）；M0分期和M1分期吻合口漏的发生率分别为5.04%和21.05%（P=0.022，OR=5.022，95%CI：1.44~17.47）；吻合口漏组和非吻合口漏组的肿瘤最大直径的平均值分别为（5.00±2.75）cm和（4.00±2.00）cm（P=0.041）。结论：直肠癌Dixon术后吻合口漏的发生与肿瘤的位置、肿瘤的最大直径、肿瘤的M分期等因素相关。

Objective: To investigate the incidence of anastomotic leakage(AL)after Dixon operation for rectal cancer,and to research its influencing factors. Methods: The clinical data of 257 patients with rectal cancer who underwent Dixon operation between January 2005 to August 2015 were collected to analysis the influencing factors for AL. Results: AL occurred in 16 patiens,and its occurrence rate was 6.23%.The rate of AL in patients with tumor above and below peritoneal reflection was 0 and 8.89%,respectively (P=0.016);the rate of AL in patients with tumor of M0 stage and M1 stage was 5.04% and 21.05%, respectively(P=0.022,OR=5.022,95%CI: 1.44~17.47); The average value of the largest tumor diameter was (5.00±2.75)cm and (4.00±2.00)cm in the leakage and nonleakage groups, respectively (P=0.041). Conclusion: AL after Dixon operation for rectal cancer is related to tumor's location, maximum diametre and M stage.

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