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直肠癌Dixon术后吻合口漏影响因素的分析
作者:王成龙1  汤文浩2 
单位:1. 南通大学医学院附属南京江北人民医院 普外科, 江苏 南京 210048;
2. 东南大学附属中大医院 普外科, 江苏 南京 210009
关键词:直肠癌 Dixon术 吻合口漏 影响因素 
分类号:R619.9
出版年·卷·期(页码):2017·36·第六期(958-961)
摘要:

目的:调查直肠癌Dixon术后吻合口漏的发生情况,研究其发生的影响因素。方法:搜集2005年1月至2015年8月因直肠癌行Dixon术的257例患者的临床资料,分析术后吻合口漏发生的影响因素。结果:257例行直肠癌Dixon术的患者中术后发生吻合口漏16例,发生率为6.23%。其中,肿瘤位于腹膜返折以上和以下吻合口漏的发生率分别为0和8.89%(P=0.016);M0分期和M1分期吻合口漏的发生率分别为5.04%和21.05%(P=0.022,OR=5.022,95%CI:1.44~17.47);吻合口漏组和非吻合口漏组的肿瘤最大直径的平均值分别为(5.00±2.75)cm和(4.00±2.00)cm(P=0.041)。结论:直肠癌Dixon术后吻合口漏的发生与肿瘤的位置、肿瘤的最大直径、肿瘤的M分期等因素相关。

Objective: To investigate the incidence of anastomotic leakage(AL)after Dixon operation for rectal cancer,and to research its influencing factors. Methods: The clinical data of 257 patients with rectal cancer who underwent Dixon operation between January 2005 to August 2015 were collected to analysis the influencing factors for AL. Results: AL occurred in 16 patiens,and its occurrence rate was 6.23%.The rate of AL in patients with tumor above and below peritoneal reflection was 0 and 8.89%,respectively (P=0.016);the rate of AL in patients with tumor of M0 stage and M1 stage was 5.04% and 21.05%, respectively(P=0.022,OR=5.022,95%CI: 1.44~17.47); The average value of the largest tumor diameter was (5.00±2.75)cm and (4.00±2.00)cm in the leakage and nonleakage groups, respectively (P=0.041). Conclusion: AL after Dixon operation for rectal cancer is related to tumor's location, maximum diametre and M stage.

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