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蛛网膜下腔出血后早期脑损伤的发病机制及治疗管理
作者:周培1  王嵘2 
单位:1. 东南大学 医学院, 江苏 南京 210009;
2. 南京大学医学院附属鼓楼医院 神经外科, 江苏 南京 210008
关键词:早期脑损伤 脑缺血 蛛网膜下腔出血 细胞凋亡 综述 
分类号:R743.35
出版年·卷·期(页码):2016·35·第五期(809-812)
摘要:

蛛网膜下腔出血作为一种有很高的发病率和致死率的疾病,目前虽然在其治疗上取得了许多创新,但是在神经系统预后方面仍无显著改善。早期脑损伤指在蛛网膜下腔出血后72 h内产生的病理生理学机制的改变,表现为颅内压的升高、颅内灌注压的降低、脑积水的产生、全脑缺血的发生、血脑屏障的破坏及脑细胞的死亡。对其治疗包括急性期治疗、确定性治疗、药物性治疗、亚低温治疗及高压氧治疗等。本文作者就动脉瘤性蛛网膜下腔出血的研究进展作一综述。

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