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南京地区结直肠癌筛查初步结果分析
作者:章秀  刘萍  林慧萍  金黑鹰  冷强  王小峰 
单位:南京中医药大学第三附属医院 全国肛肠医疗中心,江苏 南京 210001
关键词:结直肠癌 筛查 大便隐血试验 结肠镜 
分类号:R735.34
出版年·卷·期(页码):2012·31·第五期(571-573)
摘要:

目的:对南京地区结直肠癌筛查的初步结果进行分析。方法:采用粪便隐血试验联合结肠镜检查在南京地区进行结直肠癌的筛查。结果:1年内共开展筛查850例,其中初筛阳性并行结肠镜检查者722例。共诊断结直肠癌37例,结直肠息肉222例,结直肠其他病变170例。37例结直肠癌患者中15例于我院手术切除,病理分期均为Ⅰ期。对临床症状与肿瘤相关性进行Logistic回归分析显示,便血及便秘与结直肠癌存在高度相关性。结论:筛查能够提高结直肠良性肿瘤及早期肠癌的诊断率,应该对一般人群尤其是存在便血及便秘的人群积极开展结直肠癌的筛查。

Objective: To analysis the primary outcomes of colorectal cancer(CRC) screening in Nanjing. Methods: A CRC screening program was started from January 2010 by using feces occult blood test(FOBT) and colonoscopy in Nanjing. All the people older than 40 yrs or the younger ones who had cancer family history were encouraged to join the screening. Results: Overall 850 participants took part in the screening, 722 participants who had FOBT positive were screened by colonoscopy. After the colonoscopy, 37 participants were diagnosed with CRC, and 222 participants were detected with polyps, and 170 participants were diagnosed with other benign colorectal diseases. 15 of the CRC patients who had surgery in our center all had pathological degree of one degree. The Logistic regress analysis of the relationship between symptoms and colorectal tumors showed that rectal bleeding and constipation could indicate the CRC. Conclusion: Screening is an effective strategy for reducing the morbility and mortality of CRC. It is necessary to carry out CRC screening in average risk population especially the ones with rectal bleeding or constipation.

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